2009年2月8日星期日

The consequences of GERD

The stomach secretes hydrochloric acid. Of course, the mucosa is protected against the aggression of this highly corrosive acid. This is not the case of the esophageal mucosa, irritated and even burned her. Moreover, the esophagus bear any evil aggression chemical and liquid alkali (the opposite of acid) attack as well as acids (it is so bile, alkaline). The achievement of the esophageal mucosa, peptic esophagitis called, is more or less extended in height and depth: it is classified into three stages, from simple redness real digging ulcer. This burning repeated, frequent, if it can be intense, affect esophageal muscle, underlies the mucosa, and even on adjacent tissues. There is thus narrowing of the esophagus (strictures), more or less scarring, and even shortening of the esophagus, "shrunken", set by a major inflammatory reaction to adjacent structures.This is, of course, complicated and advanced stages of the disease. It also happens that the "stripping" repeated the mucosa, leading to accelerated regrowth, is followed by abnormal regeneration said mucosa of Barrett mucosa.This OBC has a tendency to degenerate into cancer: about 10% of cases after several years of evolution.

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