2009年2月9日星期一

The treatment of GERD

The so-called "dietary" must never be neglected in case of weight loss overweight, avoiding meals, do not lie down after meals, reducing the consumption of foods that retard gastric evacuation (fats, alcohol) may be sufficient for the disappearance of the signs of mild forms. The drugs are used when these measures prove insufficient. They fall into three groups: Dressings, prokinetic, anti-secretory. Dressings lining the esophageal mucosa, protecting it from acid attack. The prokinetic improve hunting, for the esophagus, its contents, including reflux. The anti-secretory drugs are most effective, most used. There are two kinds, anti H2 (Azantac, Tagamet) and inhibitors of proton pump (PPI), newer, more powerful, blocking almost completely the secretion of stomach acid (Mopral, Inipomp, Zoltum ...). These three different classes of medications can be taken separately or, more often associated. The effectiveness of these treatments is such that, in the majority of patients, almost totaled signs of GERD disappears like magic. But for some, the effect seems depleted over the years, the symptoms reappeared or worsened despite treatment. Among others, the need for continued treatment at high doses, which involves precisely the indefinite continuation of medication taken and led to seek another solution. Finally, sometimes the existence of complications, persistent ulceration despite treatment, a narrowing, a EBOs require a more radical and definitive.

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